Pseudomonas aeruginosa PAO1, PA3718

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3718
Name
Replicon chromosome
Genomic location 4164330 - 4165571 (- strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_252407.1
GI 15598913
Affymetrix PA3718_at
Entrez 880375
GenBank AAG07105.1
INSDC AAG07105.1
NCBI Locus Tag PA3718
protein_id(GenBank) gb|AAG07105.1|AE004791_2|gnl|PseudoCAP|PA3718
TIGR NTL03PA03718
UniParc UPI00000C5AD9
UniProtKB Acc Q9HXS3
UniProtKB ID Q9HXS3_PSEAE
UniRef100 UniRef100_Q9HXS3
UniRef50 UniRef50_Q9HXS3
UniRef90 UniRef90_Q9HXS3

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 9.89
Kyte-Doolittle Hydrophobicity Value 0.985
Molecular Weight (kDa) 42.3
Isoelectric Point (pI) 11.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 153 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001965 (321 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3718

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295