Pseudomonas aeruginosa PAO1, PA3725 (recJ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3725
Name
recJ
Replicon chromosome
Genomic location 4170770 - 4172485 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252414.1
GI 15598920
Affymetrix PA3725_recJ_at
Entrez 880369
GenBank AAG07112.1
INSDC AAG07112.1
NCBI Locus Tag PA3725
protein_id(GenBank) gb|AAG07112.1|AE004791_9|gnl|PseudoCAP|PA3725
TIGR NTL03PA03725
UniParc UPI00000C5ADF
UniProtKB Acc Q9HXR7
UniProtKB ID Q9HXR7_PSEAE
UniRef100 UniRef100_Q9HXR7
UniRef50 UniRef50_Q5NZT9
UniRef90 UniRef90_A6V144

Product

Feature Type CDS
Coding Frame 1
Product Name
single-stranded-DNA-specific exonuclease RecJ
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -9.02
Kyte-Doolittle Hydrophobicity Value 0.008
Molecular Weight (kDa) 62.3
Isoelectric Point (pI) 5.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 513 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001958 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3725
Search term: recJ

Human Homologs

References

Identification and purification of a single-stranded-DNA-specific exonuclease encoded by the recJ gene of Escherichia coli.
Lovett ST, Kolodner RD
Proc Natl Acad Sci U S A 1989 Apr;86(8):2627-31
PubMed ID: 2649886
Mismatch repair in Escherichia coli cells lacking single-strand exonucleases ExoI, ExoVII, and RecJ.
Harris RS, Ross KJ, Lombardo MJ, Rosenberg SM
J Bacteriol 1998 Feb;180(4):989-93
PubMed ID: 9473057