Pseudomonas aeruginosa PAO1, PA3738 (xerD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3738
Name
xerD
Replicon chromosome
Genomic location 4190616 - 4191512 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252427.1
GI 15598933
Affymetrix PA3738_xerD_at
DNASU PaCD00007631
Entrez 880331
GenBank AAG07125.1
INSDC AAG07125.1
NCBI Locus Tag PA3738
protein_id(GenBank) gb|AAG07125.1|AE004793_2|gnl|PseudoCAP|PA3738
TIGR NTL03PA03738
UniParc UPI00000C5AE9
UniProtKB Acc Q9HXQ6
UniProtKB ID XERD_PSEAE
UniRef100 UniRef100_Q9HXQ6
UniRef50 UniRef50_Q9KPE9
UniRef90 UniRef90_Q9HXQ6

Product

Feature Type CDS
Coding Frame 1
Product Name
integrase/recombinase XerD
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 4.31
Kyte-Doolittle Hydrophobicity Value -0.298
Molecular Weight (kDa) 33.6
Isoelectric Point (pI) 8.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 625 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001944 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3738
Search term: xerD

Human Homologs

References

Two related recombinases are required for site-specific recombination at dif and cer in E. coli K12.
Blakely G, May G, McCulloch R, Arciszewska LK, Burke M, Lovett ST, Sherratt DJ
Cell 1993 Oct 22;75(2):351-61
PubMed ID: 8402918