Pseudomonas aeruginosa PAO1, PA3768

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3768
Name
Replicon chromosome
Genomic location 4224107 - 4225498 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252457.1
GI 15598963
Affymetrix PA3768_at
Entrez 880551
GenBank AAG07155.1
INSDC AAG07155.1
NCBI Locus Tag PA3768
protein_id(GenBank) gb|AAG07155.1|AE004795_7|gnl|PseudoCAP|PA3768
TIGR NTL03PA03768
UniParc UPI00000C5B01
UniProtKB Acc Q9HXM7
UniProtKB ID Q9HXM7_PSEAE
UniRef100 UniRef100_K1DUL0
UniRef50 UniRef50_Q886W9
UniRef90 UniRef90_A6V0Z7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable metallo-oxidoreductase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.26
Kyte-Doolittle Hydrophobicity Value -0.305
Molecular Weight (kDa) 51.4
Isoelectric Point (pI) 6.62

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 338 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001913 (528 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3768

Human Homologs

Ensembl 110, assembly GRCh38.p14
hephaestin [Source:HGNC Symbol;Acc:HGNC:4866]
E-value: 5.0e-06
Percent Identity: 35.9
Ensembl 110, assembly GRCh38.p14
hephaestin [Source:HGNC Symbol;Acc:HGNC:4866]
E-value: 5.0e-06
Percent Identity: 35.9
Ensembl 110, assembly GRCh38.p14
hephaestin [Source:HGNC Symbol;Acc:HGNC:4866]
E-value: 5.0e-06
Percent Identity: 35.9
Ensembl 110, assembly GRCh38.p14
hephaestin [Source:HGNC Symbol;Acc:HGNC:4866]
E-value: 5.0e-06
Percent Identity: 35.9
Ensembl 110, assembly GRCh38.p14
hephaestin [Source:HGNC Symbol;Acc:HGNC:4866]
E-value: 5.0e-06
Percent Identity: 35.9
Ensembl 110, assembly GRCh38.p14
hephaestin [Source:HGNC Symbol;Acc:HGNC:4866]
E-value: 5.0e-06
Percent Identity: 35.9
Ensembl 110, assembly GRCh38.p14
hephaestin [Source:HGNC Symbol;Acc:HGNC:4866]
E-value: 5.0e-06
Percent Identity: 35.9

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295