Pseudomonas aeruginosa PAO1, PA3811 (hscB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3811
Name
hscB
Replicon chromosome
Genomic location 4269619 - 4270140 (- strand)

Cross-References

RefSeq NP_252500.1
GI 15599006
Affymetrix PA3811_hscB_at
DNASU PaCD00007659
Entrez 879937
GenBank AAG07198.1
INSDC AAG07198.1
NCBI Locus Tag PA3811
protein_id(GenBank) gb|AAG07198.1|AE004799_4|gnl|PseudoCAP|PA3811
TIGR NTL03PA03811
UniParc UPI00000C5B20
UniProtKB Acc Q9HXJ1
UniProtKB ID HSCB_PSEAE
UniRef100 UniRef100_B7UWI0
UniRef50 UniRef50_Q886Z8
UniRef90 UniRef90_B7UWI0

Product

Feature Type CDS
Coding Frame 1
Product Name
heat shock protein HscB
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -9.33
Kyte-Doolittle Hydrophobicity Value -0.658
Molecular Weight (kDa) 20.2
Isoelectric Point (pI) 4.64

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 112 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001855 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3811
Search term: hscB

Human Homologs

References

The Pseudomonas aeruginosa hscA gene encodes Hsc66, a DnaK homologue.
Campos-García J, G Ordóñez L, Soberón-Chávez G
Microbiology 2000 Jun;146 ( Pt 6):1429-35
PubMed ID: 10846221
Assembly of iron-sulfur clusters. Identification of an iscSUA-hscBA-fdx gene cluster from Azotobacter vinelandii.
Zheng L, Cash VL, Flint DH, Dean DR
J Biol Chem 1998 May 22;273(21):13264-72
PubMed ID: 9582371