Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3825
|
Name |
|
Replicon | chromosome |
Genomic location | 4282078 - 4283658 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_252514.1 |
GI | 15599020 |
Affymetrix | PA3825_at |
Entrez | 879846 |
GenBank | AAG07212.1 |
INSDC | AAG07212.1 |
NCBI Locus Tag | PA3825 |
protein_id(GenBank) | gb|AAG07212.1|AE004800_1|gnl|PseudoCAP|PA3825 |
TIGR | NTL03PA03825 |
UniParc | UPI00000C5B2A |
UniProtKB Acc | Q9HXH7 |
UniProtKB ID | Q9HXH7_PSEAE |
UniRef100 | UniRef100_Q9HXH7 |
UniRef50 | UniRef50_A0A0B7DC83 |
UniRef90 | UniRef90_Q9HXH7 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Cyclic-guanylate-specific phosphodiesterase
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -6.75 |
Kyte-Doolittle Hydrophobicity Value | 0.032 |
Molecular Weight (kDa) | 58.3 |
Isoelectric Point (pI) | 5.87 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
5MKG | HYDROLASE | 12/04/16 | PA3825-EAL Ca-CdG Structure | Pseudomonas aeruginosa | 2.44 | X-RAY DIFFRACTION | 100.0 |
4Y9O | UNKNOWN FUNCTION | 02/17/15 | PA3825-EAL Metal-Free-Apo Structure - Manganese Co-crystallisation | Pseudomonas aeruginosa PAO1 | 1.81 | X-RAY DIFFRACTION | 99.6 |
4Y9M | UNKNOWN FUNCTION | 02/17/15 | PA3825-EAL Metal-Free-Apo Structure | Pseudomonas aeruginosa PAO1 | 1.6 | X-RAY DIFFRACTION | 100.0 |
5MF5 | HYDROLASE | 11/17/16 | PA3825-EAL Mg-CdG Structure | Pseudomonas aeruginosa | 1.77 | X-RAY DIFFRACTION | 99.6 |
4Y8E | METAL BINDING PROTEIN | 02/16/15 | PA3825-EAL Ca-Apo Structure | Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) | 1.61 | X-RAY DIFFRACTION | 100.0 |
5MFU | HYDROLASE | 11/18/16 | PA3825-EAL Mn-pGpG Structure | Pseudomonas aeruginosa | 2.15 | X-RAY DIFFRACTION | 100.0 |
4Y9P | SIGNALING PROTEIN | 02/17/15 | PA3825-EAL Ca-CdG Structure | Pseudomonas aeruginosa PAO1 | 2.44 | X-RAY DIFFRACTION | 100.0 |
4Y9N | UNKNOWN FUNCTION | 02/17/15 | PA3825-EAL Metal-Free-Apo Structure - Magnesium Co-crystallisation | Pseudomonas aeruginosa PAO1 | 1.92 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 403 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001840 (462 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3825
Search term: Cyclic-guanylate-specific phosphodiesterase
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence.
Kulasakara H, Lee V, Brencic A, Liberati N, Urbach J, Miyata S, Lee DG, Neely AN, Hyodo M, Hayakawa Y, Ausubel FM, Lory S
Proc Natl Acad Sci U S A 2006 Feb 21;103(8):2839-44
PubMed ID: 16477007
|