Pseudomonas aeruginosa PAO1, PA3860

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3860
Name
Replicon chromosome
Genomic location 4318922 - 4320820 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_252549.1
GI 15599055
Affymetrix PA3860_at
Entrez 879803
GenBank AAG07247.1
INSDC AAG07247.1
NCBI Locus Tag PA3860
protein_id(GenBank) gb|AAG07247.1|AE004803_3|gnl|PseudoCAP|PA3860
TIGR NTL03PA03860
UniParc UPI00000C5B48
UniProtKB Acc Q9HXE6
UniProtKB ID Q9HXE6_PSEAE
UniRef100 UniRef100_Q9HXE6
UniRef50 UniRef50_W6QZJ8
UniRef90 UniRef90_A0A022NTY5

Product

Feature Type CDS
Coding Frame 1
Product Name
probable AMP-binding enzyme
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -10.16
Kyte-Doolittle Hydrophobicity Value -0.124
Molecular Weight (kDa) 69.0
Isoelectric Point (pI) 6.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 604 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001809 (341 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3860

Human Homologs

Ensembl 110, assembly GRCh38.p14
acyl-CoA synthetase medium chain family member 1 [Source:HGNC Symbol;Acc:HGNC:18049]
E-value: 2.2e-36
Percent Identity: 27.6
Ensembl 110, assembly GRCh38.p14
acyl-CoA synthetase medium chain family member 1 [Source:HGNC Symbol;Acc:HGNC:18049]
E-value: 2.2e-36
Percent Identity: 27.6

References

No references are associated with this feature.