Pseudomonas aeruginosa PAO1, PA3890 (opuCB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3890
Name
opuCB
Replicon chromosome
Genomic location 4356201 - 4356863 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs
CommentBroad-spectrum QAC-transporter activated by hyperosmolarity
CommentBroad-spectrum QAC-transporter activated by hyperosmolarity

Cross-References

RefSeq NP_252579.1
GI 15599085
Affymetrix PA3890_at
DNASU PaCD00007695
Entrez 878812
GenBank AAG07277.1
INSDC AAG07277.1
NCBI Locus Tag PA3890
protein_id(GenBank) gb|AAG07277.1|AE004806_4|gnl|PseudoCAP|PA3890
TIGR NTL03PA03890
UniParc UPI00000C5B5E
UniProtKB Acc Q9HXC3
UniProtKB ID Q9HXC3_PSEAE
UniRef100 UniRef100_S0J7M9
UniRef50 UniRef50_Q8ZPK3
UniRef90 UniRef90_S0J7M9

Product

Feature Type CDS
Coding Frame 1
Product Name
OpuC ABC transporter, permease protein, OpuCB
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 4.70
Kyte-Doolittle Hydrophobicity Value 1.157
Molecular Weight (kDa) 23.2
Isoelectric Point (pI) 10.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 396 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001780 (493 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3890
Search term: opuCB

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Characterization of a chimeric proU operon in a subtilin-producing mutant of Bacillus subtilis 168.
Lin Y, Hansen JN
J Bacteriol 1995 Dec;177(23):6874-80
PubMed ID: 7592481
Characterization of the osmoprotectant transporter OpuC from Pseudomonas syringae and demonstration that cystathionine-beta-synthase domains are required for its osmoregulatory function.
Chen C, Beattie GA
J Bacteriol 2007 Oct;189(19):6901-12
PubMed ID: 17660277