Pseudomonas aeruginosa PAO1, PA3902

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3902
Name
Replicon chromosome
Genomic location 4371287 - 4371748 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252591.1
GI 15599097
Affymetrix PA3902_at
DNASU PaCD00007701
Entrez 878927
GenBank AAG07289.1
INSDC AAG07289.1
NCBI Locus Tag PA3902
protein_id(GenBank) gb|AAG07289.1|AE004807_8|gnl|PseudoCAP|PA3902
TIGR NTL03PA03902
UniParc UPI000012DA8D
UniProtKB Acc Q9HXB1
UniProtKB ID IVY_PSEAE
UniRef100 UniRef100_Q9HXB1
UniRef50 UniRef50_Q9HXB1
UniRef90 UniRef90_Q9HXB1

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by two-dimensional gel electrophoresis and mass spectral analysis(PMID:21863142).
Detected by two-dimensional gel electrophoresis (PMID:21863142).
Detected by iTRAQ (PMID:21863142).
Charge (pH 7) -0.35
Kyte-Doolittle Hydrophobicity Value -0.478
Molecular Weight (kDa) 16.9
Isoelectric Point (pI) 6.78

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4PS6 TOXIN 03/06/14 Crystal structure of an inhibitor of vertebrate lysozyme (PA3902) from Pseudomonas aeruginosa PAO1 at 1.25 A resolution Pseudomonas aeruginosa 1.25 X-RAY DIFFRACTION 100.0
1UUZ HYDROLASE/INHIBITOR 01/12/04 IVY:A NEW FAMILY OF PROTEIN GALLUS GALLUS; PSEUDOMONAS AERUGINOSA 1.8 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 19 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001773 (299 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3902

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.
Rao J, Damron FH, Basler M, Digiandomenico A, Sherman NE, Fox JW, Mekalanos JJ, Goldberg JB
Front Microbiol 2011;2:162
PubMed ID: 21863142