Pseudomonas aeruginosa PAO1, PA3906

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3906
Name
Replicon chromosome
Genomic location 4374850 - 4375233 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
CommentPAAR4, TecT and co-TecT are required for TseT-mediated killing.
CommentTecT and co-TecT form a complex that dissociates upon PAAR4 binding to TecT.

Cross-References

RefSeq NP_252595.1
GI 15599101
Affymetrix PA3906_at
DNASU PaCD00007704
Entrez 878940
GenBank AAG07293.1
INSDC AAG07293.1
NCBI Locus Tag PA3906
protein_id(GenBank) gb|AAG07293.1|AE004808_3|gnl|PseudoCAP|PA3906
TIGR NTL03PA03906
UniParc UPI00000C5B6C
UniProtKB Acc Q9HXA7
UniProtKB ID Q9HXA7_PSEAE
UniRef100 UniRef100_W0YXT5
UniRef50 UniRef50_I4XVX2
UniRef90 UniRef90_W0YXT5

Product

Feature Type CDS
Coding Frame 1
Product Name
co-chaperone, co-TecT
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -2.52
Kyte-Doolittle Hydrophobicity Value -0.445
Molecular Weight (kDa) 14.8
Isoelectric Point (pI) 5.32

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 2 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001770 (310 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3906

Human Homologs

References

A type VI secretion system effector delivery mechanism dependent on PAAR and a chaperone-co-chaperone complex.
Burkinshaw BJ, Liang X, Wong M, Le ANH, Lam L, Dong TG
Nat Microbiol 2018 May;3(5):632-640
PubMed ID: 29632369