Pseudomonas aeruginosa PAO1, PA4037

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4037
Name
Replicon chromosome
Genomic location 4519275 - 4520201 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252726.1
GI 15599232
Affymetrix PA4037_at
DNASU PaCD00007762
Entrez 879032
GenBank AAG07424.1
INSDC AAG07424.1
NCBI Locus Tag PA4037
protein_id(GenBank) gb|AAG07424.1|AE004820_9|gnl|PseudoCAP|PA4037
TIGR NTL03PA04037
UniParc UPI00000C5BD4
UniProtKB Acc Q9HWZ0
UniProtKB ID Q9HWZ0_PSEAE
UniRef100 UniRef100_W0W9V6
UniRef50 UniRef50_A6V069
UniRef90 UniRef90_A6V069

Product

Feature Type CDS
Coding Frame 1
Product Name
probable ATP-binding component of ABC transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.63
Kyte-Doolittle Hydrophobicity Value -0.210
Molecular Weight (kDa) 34.0
Isoelectric Point (pI) 9.75

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001647 (303 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4037

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:32]
E-value: 4.6e-32
Percent Identity: 29.5
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:32]
E-value: 4.6e-32
Percent Identity: 29.5
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:32]
E-value: 4.6e-32
Percent Identity: 29.5
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:32]
E-value: 4.6e-32
Percent Identity: 29.5
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:32]
E-value: 4.6e-32
Percent Identity: 29.5

References

Cloning and characterization of the Flavobacterium johnsoniae (Cytophaga johnsonae) gliding motility gene, gldA.
Agarwal S, Hunnicutt DW, McBride MJ
Proc Natl Acad Sci U S A 1997 Oct 28;94(22):12139-44
PubMed ID: 9342376