Pseudomonas aeruginosa PAO1, PA4056 (ribD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4056
Name
ribD
Synonym: ribG
Replicon chromosome
Genomic location 4536921 - 4538042 (- strand)

Cross-References

RefSeq NP_252745.1
GI 15599251
Affymetrix PA4056_ribD_at
DNASU PaCD00007774
Entrez 879079
GenBank AAG07443.1
INSDC AAG07443.1
NCBI Locus Tag PA4056
protein_id(GenBank) gb|AAG07443.1|AE004822_3|gnl|PseudoCAP|PA4056
TIGR NTL03PA04056
UniParc UPI00000C5BE3
UniProtKB Acc Q9HWX2
UniProtKB ID Q9HWX2_PSEAE
UniRef100 UniRef100_Q9HWX2
UniRef50 UniRef50_Q9HWX2
UniRef90 UniRef90_Q9HWX2

Product

Feature Type CDS
Coding Frame 1
Product Name
riboflavin-specific deaminase/reductase
Product Name Confidence: Class 2
Synonyms riboflavin biosynthetic protein RibG
bifunctional pyrimidine deaminase/reductase in pathway of riboflavin biosynthesis
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.05
Kyte-Doolittle Hydrophobicity Value 0.019
Molecular Weight (kDa) 39.8
Isoelectric Point (pI) 7.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 613 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001628 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4056
Search term: ribD

Human Homologs

References

[Riboflavin biosynthesis genes of Bacillus subtilis--complete primary structure and organization model].
Mironov VN, Kraev AS, Chernov BK, Ul'ianov AV, Golova IuB
Dokl Akad Nauk SSSR 1989;305(2):482-7
PubMed ID: 2501076
Functional organization of the riboflavin biosynthesis operon from Bacillus subtilis SHgw.
Mironov VN, Kraev AS, Chikindas ML, Chernov BK, Stepanov AI, Skryabin KG
Mol Gen Genet 1994 Jan;242(2):201-8
PubMed ID: 8159171
The complete genome sequence of Escherichia coli K-12.
Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y
Science 1997 Sep 5;277(5331):1453-62
PubMed ID: 9278503