Pseudomonas aeruginosa PAO1, PA4064

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4064
Name
Replicon chromosome
Genomic location 4541951 - 4542655 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252753.1
GI 15599259
Affymetrix PA4064_at
Entrez 878673
GenBank AAG07451.1
INSDC AAG07451.1
NCBI Locus Tag PA4064
protein_id(GenBank) gb|AAG07451.1|AE004822_11|gnl|PseudoCAP|PA4064
TIGR NTL03PA04064
UniParc UPI00000C5BEA
UniProtKB Acc Q9HWW4
UniProtKB ID Q9HWW4_PSEAE
UniRef100 UniRef100_W0YWD6
UniRef50 UniRef50_Q0C5S3
UniRef90 UniRef90_A6V039

Product

Feature Type CDS
Coding Frame 1
Product Name
probable ATP-binding component of ABC transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.86
Kyte-Doolittle Hydrophobicity Value -0.131
Molecular Weight (kDa) 25.4
Isoelectric Point (pI) 7.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001621 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4064

Human Homologs

Ensembl 110, assembly GRCh38.p14
transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43]
E-value: 2.5e-14
Percent Identity: 31.4
Ensembl 110, assembly GRCh38.p14
transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43]
E-value: 2.5e-14
Percent Identity: 31.4
Ensembl 110, assembly GRCh38.p14
transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43]
E-value: 2.5e-14
Percent Identity: 31.4
Ensembl 110, assembly GRCh38.p14
transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43]
E-value: 2.5e-14
Percent Identity: 31.4
Ensembl 110, assembly GRCh38.p14
transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43]
E-value: 2.5e-14
Percent Identity: 31.4
Ensembl 110, assembly GRCh38.p14
transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43]
E-value: 2.5e-14
Percent Identity: 31.4
Ensembl 110, assembly GRCh38.p14
transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43]
E-value: 2.5e-14
Percent Identity: 31.4
Ensembl 110, assembly GRCh38.p14
transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43]
E-value: 2.5e-14
Percent Identity: 31.4
Ensembl 110, assembly GRCh38.p14
transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43]
E-value: 2.5e-14
Percent Identity: 31.4

References

A set of ordered cosmids and a detailed genetic and physical map for the 8 Mb Streptomyces coelicolor A3(2) chromosome.
Redenbach M, Kieser HM, Denapaite D, Eichner A, Cullum J, Kinashi H, Hopwood DA
Mol Microbiol 1996 Jul;21(1):77-96
PubMed ID: 8843436