Pseudomonas aeruginosa PAO1, PA4080

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4080
Name
Synonym: rcsB
Replicon chromosome
Genomic location 4559006 - 4559650 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252769.1
GI 15599275
Affymetrix PA4080_at
Entrez 878667
GenBank AAG07467.1
INSDC AAG07467.1
NCBI Locus Tag PA4080
protein_id(GenBank) gb|AAG07467.1|AE004824_2|gnl|PseudoCAP|PA4080
TIGR NTL03PA04080
UniParc UPI00000C5BFA
UniProtKB Acc Q9HWU8
UniProtKB ID Q9HWU8_PSEAE
UniRef100 UniRef100_W0YY96
UniRef50 UniRef50_A9AQJ5
UniRef90 UniRef90_A0A080VSP7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable response regulator
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 5.31
Kyte-Doolittle Hydrophobicity Value -0.035
Molecular Weight (kDa) 23.7
Isoelectric Point (pI) 8.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 467 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001606 (736 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4080

Human Homologs

References

Characterization of rcsB and rcsC from Escherichia coli O9:K30:H12 and examination of the role of the rcs regulatory system in expression of group I capsular polysaccharides.
Jayaratne P, Keenleyside WJ, MacLachlan PR, Dodgson C, Whitfield C
J Bacteriol 1993 Sep;175(17):5384-94
PubMed ID: 8366025
A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map.
Itoh T, Aiba H, Baba T, Hayashi K, Inada T, Isono K, Kasai H, Kimura S, Kitakawa M, Kitagawa M, Makino K, Miki T, Mizobuchi K, Mori H, Mori T, Motomura K, Nakade S, Nakamura Y, Nashimoto H, Nishio Y, Oshima T, Saito N, Sampei G, Seki Y, Horiuchi T
DNA Res 1996 Dec 31;3(6):379-92
PubMed ID: 9097040