Pseudomonas aeruginosa PAO1, PA4082 (cupB5)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4082
Name
cupB5
Replicon chromosome
Genomic location 4561540 - 4564596 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252771.1
GI 15599277
Affymetrix PA4082_at
Entrez 878708
GenBank AAG07469.1
INSDC AAG07469.1
NCBI Locus Tag PA4082
protein_id(GenBank) gb|AAG07469.1|AE004824_4|gnl|PseudoCAP|PA4082
TIGR NTL03PA04082
UniParc UPI00000C5BFC
UniProtKB Acc Q9HWU6
UniProtKB ID Q9HWU6_PSEAE
UniRef100 UniRef100_Q9HWU6
UniRef50 UniRef50_Q9HWU6
UniRef90 UniRef90_Q9HWU6

Product

Feature Type CDS
Coding Frame 1
Product Name
adhesive protein CupB5
Product Name Confidence: Class 2
Synonyms probable adhesin
Evidence for Translation
Charge (pH 7) 4.05
Kyte-Doolittle Hydrophobicity Value 0.074
Molecular Weight (kDa) 100.4
Isoelectric Point (pI) 8.09

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 142 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001605 (334 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4082
Search term: cupB5

Human Homologs

References

Cloning, expression, and DNA sequence analysis of genes encoding nontypeable Haemophilus influenzae high-molecular-weight surface-exposed proteins related to filamentous hemagglutinin of Bordetella pertussis.
Barenkamp SJ, Leininger E
Infect Immun 1992 Apr;60(4):1302-13
PubMed ID: 1548058