Pseudomonas aeruginosa PAO1, PA4086 (cupB1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4086
Name
cupB1
Replicon chromosome
Genomic location 4569054 - 4569623 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq NP_252775.1
GI 15599281
Affymetrix PA4086_at
Entrez 878758
GenBank AAG07473.1
INSDC AAG07473.1
NCBI Locus Tag PA4086
protein_id(GenBank) gb|AAG07473.1|AE004825_2|gnl|PseudoCAP|PA4086
TIGR NTL03PA04086
UniParc UPI00000C5C00
UniProtKB Acc Q9HWU2
UniProtKB ID Q9HWU2_PSEAE
UniRef100 UniRef100_Q9HWU2
UniRef50 UniRef50_Q4KGP4
UniRef90 UniRef90_Q9HWU2

Product

Feature Type CDS
Coding Frame 1
Product Name
probable fimbrial subunit CupB1
Product Name Confidence: Class 2
Synonyms probable pilin
Evidence for Translation
Charge (pH 7) 2.40
Kyte-Doolittle Hydrophobicity Value 0.190
Molecular Weight (kDa) 19.7
Isoelectric Point (pI) 8.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Fimbrial
Note: This is based on PSORTb V3.0 secondary localization prediction
 Class 3
Unknown Class 3
Extracellular Class 3
Fimbrial Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 31 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000955 (1577 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4086
Search term: cupB1

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295