Pseudomonas aeruginosa PAO1, PA4126

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4126
Name
Synonym: hpaX
Replicon chromosome
Genomic location 4614024 - 4615328 (+ strand)
Transposon Mutants 9 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252815.1
GI 15599321
Affymetrix PA4126_at
Entrez 878650
GenBank AAG07513.1
INSDC AAG07513.1
NCBI Locus Tag PA4126
protein_id(GenBank) gb|AAG07513.1|AE004829_3|gnl|PseudoCAP|PA4126
TIGR NTL03PA04126
UniParc UPI00000C5C23
UniProtKB Acc Q9HWQ5
UniProtKB ID Q9HWQ5_PSEAE
UniRef100 UniRef100_A0A081HJP7
UniRef50 UniRef50_Q5GTU8
UniRef90 UniRef90_A0A081HJP7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 6.52
Kyte-Doolittle Hydrophobicity Value 0.741
Molecular Weight (kDa) 47.2
Isoelectric Point (pI) 8.95

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 278 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001573 (493 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4126

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
Prieto MA, Díaz E, García JL
J Bacteriol 1996 Jan;178(1):111-20
PubMed ID: 8550403
Characterization and distribution of tartrate utilization genes in the grapevine pathogen Agrobacterium vitis.
Salomone JY, Crouzet P, De Ruffray P, Otten L
Mol Plant Microbe Interact 1996 Jul;9(5):401-8
PubMed ID: 8672817