Pseudomonas aeruginosa PAO1, PA4147 (acoR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4147
Name
acoR
Replicon chromosome
Genomic location 4639502 - 4641379 (- strand)
Transposon Mutants 9 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252836.1
GI 15599342
Affymetrix PA4147_acoR_at
Entrez 880118
GenBank AAG07534.1
INSDC AAG07534.1
NCBI Locus Tag PA4147
protein_id(GenBank) gb|AAG07534.1|AE004831_6|gnl|PseudoCAP|PA4147
TIGR NTL03PA04147
UniParc UPI00000C5C38
UniProtKB Acc Q9HWN4
UniProtKB ID Q9HWN4_PSEAE
UniRef100 UniRef100_Q9HWN4
UniRef50 UniRef50_G8QCJ5
UniRef90 UniRef90_Q9HWN4

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator AcoR
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 7.39
Kyte-Doolittle Hydrophobicity Value -0.249
Molecular Weight (kDa) 69.0
Isoelectric Point (pI) 7.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 472 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001552 (387 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4147
Search term: acoR

Human Homologs

References

Identification of acoR, a regulatory gene for the expression of genes essential for acetoin catabolism in Alcaligenes eutrophus H16.
Krüger N, Steinbüchel A
J Bacteriol 1992 Jul;174(13):4391-400
PubMed ID: 1378052