Pseudomonas aeruginosa PAO1, PA4150

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4150
Name
Synonym: acoA
Replicon chromosome
Genomic location 4643571 - 4644545 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252839.1
GI 15599345
Affymetrix PA4150_at
Entrez 880054
GenBank AAG07537.1
INSDC AAG07537.1
NCBI Locus Tag PA4150
protein_id(GenBank) gb|AAG07537.1|AE004831_9|gnl|PseudoCAP|PA4150
TIGR NTL03PA04150
UniParc UPI00000C5C3B
UniProtKB Acc Q9HWN1
UniProtKB ID Q9HWN1_PSEAE
UniRef100 UniRef100_U9I4T7
UniRef50 UniRef50_A5I2A0
UniRef90 UniRef90_A0A022P3C1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable dehydrogenase E1 component
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -14.84
Kyte-Doolittle Hydrophobicity Value -0.163
Molecular Weight (kDa) 34.6
Isoelectric Point (pI) 5.01

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database PseudoCAP
Category Not available / Not known
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Hordeum vulgare
Notes
Infection model Barley seed pathogenicity assay
Reference 21261818

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 438 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001550 (399 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4150

Human Homologs

References

Identification and molecular characterization of the Alcaligenes eutrophus H16 aco operon genes involved in acetoin catabolism.
Priefert H, Hein S, Krüger N, Zeh K, Schmidt B, Steinbüchel A
J Bacteriol 1991 Jul;173(13):4056-71
PubMed ID: 2061286
Identification and molecular characterization of the aco genes encoding the Pelobacter carbinolicus acetoin dehydrogenase enzyme system.
Oppermann FB, Steinbüchel A
J Bacteriol 1994 Jan;176(2):469-85
PubMed ID: 8110297
Molecular characterization of the Pseudomonas putida 2,3-butanediol catabolic pathway.
Huang M, Oppermann FB, Steinbüchel A
FEMS Microbiol Lett 1994 Dec 1;124(2):141-50
PubMed ID: 7813883