Pseudomonas aeruginosa PAO1, PA4151 (acoB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4151
Name
acoB
Replicon chromosome
Genomic location 4644578 - 4645597 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252840.1
GI 15599346
Affymetrix PA4151_acoB_at
DNASU PaCD00007804
Entrez 880055
GenBank AAG07538.1
INSDC AAG07538.1
NCBI Locus Tag PA4151
protein_id(GenBank) gb|AAG07538.1|AE004831_10|gnl|PseudoCAP|PA4151
TIGR NTL03PA04151
UniParc UPI00000C5C3C
UniProtKB Acc Q9HWN0
UniProtKB ID Q9HWN0_PSEAE
UniRef100 UniRef100_W0YXZ5
UniRef50 UniRef50_Q4KEQ5
UniRef90 UniRef90_A0A067A575

Product

Feature Type CDS
Coding Frame 1
Product Name
acetoin catabolism protein AcoB
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -10.76
Kyte-Doolittle Hydrophobicity Value 0.055
Molecular Weight (kDa) 36.4
Isoelectric Point (pI) 4.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 577 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001549 (405 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4151
Search term: acoB

Human Homologs

Ensembl 110, assembly GRCh38.p14
pyruvate dehydrogenase E1 subunit beta [Source:HGNC Symbol;Acc:HGNC:8808]
E-value: 1.7e-64
Percent Identity: 40.1

References

No references are associated with this feature.