Pseudomonas aeruginosa PAO1, PA4161 (fepG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4161
Name
fepG
Replicon chromosome
Genomic location 4656387 - 4657418 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252850.1
GI 15599356
Affymetrix PA4161_fepG_at
Entrez 880214
GenBank AAG07548.1
INSDC AAG07548.1
NCBI Locus Tag PA4161
protein_id(GenBank) gb|AAG07548.1|AE004832_8|gnl|PseudoCAP|PA4161
TIGR NTL03PA04161
UniParc UPI00000C5C46
UniProtKB Acc Q9HWM0
UniProtKB ID Q9HWM0_PSEAE
UniRef100 UniRef100_Q9HWM0
UniRef50 UniRef50_Q9HWM0
UniRef90 UniRef90_Q9HWM0

Product

Feature Type CDS
Coding Frame 1
Product Name
ferric enterobactin transport protein FepG
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 14.61
Kyte-Doolittle Hydrophobicity Value 0.885
Molecular Weight (kDa) 34.8
Isoelectric Point (pI) 11.93

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 548 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001541 (706 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4161
Search term: fepG

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent systems in Escherichia coli.
Shea CM, McIntosh MA
Mol Microbiol 1991 Jun;5(6):1415-28
PubMed ID: 1838574