Pseudomonas aeruginosa PAO1, PA4162

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4162
Name
Replicon chromosome
Genomic location 4657429 - 4658145 (- strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_252851.1
GI 15599357
Affymetrix PA4162_at
DNASU PaCD00007809
Entrez 880119
GenBank AAG07549.1
INSDC AAG07549.1
NCBI Locus Tag PA4162
protein_id(GenBank) gb|AAG07549.1|AE004832_9|gnl|PseudoCAP|PA4162
TIGR NTL03PA04162
UniParc UPI00000C5C47
UniProtKB Acc Q9HWL9
UniProtKB ID Q9HWL9_PSEAE
UniRef100 UniRef100_W0W7P4
UniRef50 UniRef50_K0CCH5
UniRef90 UniRef90_W0W7P4

Product

Feature Type CDS
Coding Frame 1
Product Name
probable short-chain dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.60
Kyte-Doolittle Hydrophobicity Value 0.193
Molecular Weight (kDa) 24.9
Isoelectric Point (pI) 7.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 652 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001540 (306 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4162

Human Homologs

Ensembl 110, assembly GRCh38.p14
dehydrogenase/reductase 4 [Source:HGNC Symbol;Acc:HGNC:16985]
E-value: 4.8e-21
Percent Identity: 31.9
Ensembl 110, assembly GRCh38.p14
dehydrogenase/reductase 4 [Source:HGNC Symbol;Acc:HGNC:16985]
E-value: 4.8e-21
Percent Identity: 31.9

References

No references are associated with this feature.