Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4207
|
Name |
mexI
|
Replicon | chromosome |
Genomic location | 4707535 - 4710624 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 3 transposon mutants in orthologs |
RefSeq | NP_252896.1 |
GI | 15599402 |
Affymetrix | PA4207_at |
Entrez | 880346 |
GenBank | AAG07594.1 |
INSDC | AAG07594.1 |
NCBI Locus Tag | PA4207 |
protein_id(GenBank) | gb|AAG07594.1|AE004837_5|gnl|PseudoCAP|PA4207 |
TIGR | NTL03PA04207 |
UniParc | UPI00000C5C74 |
UniProtKB Acc | Q9HWH4 |
UniProtKB ID | Q9HWH4_PSEAE |
UniRef100 | UniRef100_U8NIU1 |
UniRef50 | UniRef50_W0YY82 |
UniRef90 | UniRef90_W0YY82 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
probable Resistance-Nodulation-Cell Division (RND) efflux transporter
|
Synonyms |
probable RND efflux transporter |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -5.64 |
Kyte-Doolittle Hydrophobicity Value | 0.358 |
Molecular Weight (kDa) | 111.0 |
Isoelectric Point (pI) | 6.08 |
Individual Mappings | |
Additional evidence for subcellular localization |
Identified using the Resistance Gene Identifier (RGI)
Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
MexI | MexI is the inner membrane transporter of the efflux complex MexGHI-OpmD. [PMID:15817779, PMID:12917802] | ARO:3000808 | protein homolog model | Perfect | 1912.5 | 100.0 | 3.2.5 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001500 (799 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4207
Search term: mexI
|
Characterization of a new efflux pump, MexGHI-OpmD, from Pseudomonas aeruginosa that confers resistance to vanadium.
Aendekerk S, Ghysels B, Cornelis P, Baysse C
Microbiology (Reading) 2002 Aug;148(Pt 8):2371-2381
PubMed ID: 12177331
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa.
Köhler T, Michéa-Hamzehpour M, Henze U, Gotoh N, Curty LK, Pechère JC
Mol Microbiol 1997 Jan;23(2):345-54
PubMed ID: 9044268
|