Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4221
|
Name |
fptA
|
Replicon | chromosome |
Genomic location | 4724639 - 4726801 (- strand) |
Transposon Mutants | 4 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 4 transposon mutants in orthologs |
RefSeq | NP_252911.1 |
GI | 15599417 |
Affymetrix | PA4221_fptA_at |
Entrez | 880419 |
GenBank | AAG07609.1 |
INSDC | AAG07609.1 |
NCBI Locus Tag | PA4221 |
protein_id(GenBank) | gb|AAG07609.1|AE004839_2|gnl|PseudoCAP|PA4221 |
TIGR | NTL03PA04222 |
UniParc | UPI000012ABC9 |
UniProtKB Acc | P42512 |
UniProtKB ID | FPTA_PSEAE |
UniRef100 | UniRef100_P42512 |
UniRef50 | UniRef50_P42512 |
UniRef90 | UniRef90_P42512 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Fe(III)-pyochelin outer membrane receptor precursor
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Verified using two-dimensional gel electrophoresis, MALDI-TOF MS and peptide mass mapping(pI:5.9, molecular weight:80.0, PMID:21674802)
Detected by MALDI-TOF/TOF (PMID:19333994).
|
Charge (pH 7) | -4.85 |
Kyte-Doolittle Hydrophobicity Value | -0.554 |
Molecular Weight (kDa) | 80.0 |
Isoelectric Point (pI) | 6.11 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
1XKW | MEMBRANE PROTEIN | 09/30/04 | Pyochelin outer membrane receptor FptA from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 2 | X-RAY DIFFRACTION | 100.0 |
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
Lauryl Dimethylamine-N-Oxide | DB04147 | DrugBank | 5.1.4 | P42512 | Fe(3+)-pyochelin receptor | 100.0 | 720 | 0.0e+00 |
Source 1 | |
Database | VFDB : VF0095 |
Category | Pyochelin receptor |
Evidence |
|
Host Organism | |
Notes | |
Reference |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 250 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001486 (1037 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4221
Search term: fptA
Search term: Fe(III)-pyochelin outer membrane receptor precursor
|
FptA, the Fe(III)-pyochelin receptor of Pseudomonas aeruginosa: a phenolate siderophore receptor homologous to hydroxamate siderophore receptors.
Ankenbauer RG, Quan HN
J Bacteriol 1994 Jan;176(2):307-19
PubMed ID: 8288523
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
Proteomics of the oxidative stress response induced by hydrogen peroxide and paraquat reveals a novel AhpC-like protein in Pseudomonas aeruginosa.
Hare NJ, Scott NE, Shin EH, Connolly AM, Larsen MR, Palmisano G, Cordwell SJ
Proteomics 2011 Aug;11(15):3056-69
PubMed ID: 21674802
|