Pseudomonas aeruginosa PAO1, PA4282

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4282
Name
Synonym: sbcC
Replicon chromosome
Genomic location 4795642 - 4799277 (+ strand)
Transposon Mutants 7 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252972.1
GI 15599478
Affymetrix PA4282_at
Entrez 881690
GenBank AAG07670.1
INSDC AAG07670.1
NCBI Locus Tag PA4282
protein_id(GenBank) gb|AAG07670.1|AE004844_2|gnl|PseudoCAP|PA4282
TIGR NTL03PA04283
UniParc UPI0000135596
UniProtKB Acc Q9HWB8
UniProtKB ID SBCC_PSEAE
UniRef100 UniRef100_Q9HWB8
UniRef50 UniRef50_Q9HWB8
UniRef90 UniRef90_Q9HWB8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable exonuclease
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -23.86
Kyte-Doolittle Hydrophobicity Value -0.883
Molecular Weight (kDa) 139.0
Isoelectric Point (pI) 5.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 305 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003885 (531 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4282

Human Homologs

References

Escherichia coli sbcC mutants permit stable propagation of DNA replicons containing a long palindrome.
Chalker AF, Leach DR, Lloyd RG
Gene 1988 Nov 15;71(1):201-5
PubMed ID: 2975250
Molecular organization of sbcC, a gene that affects genetic recombination and the viability of DNA palindromes in Escherichia coli K-12.
Naom IS, Morton SJ, Leach DR, Lloyd RG
Nucleic Acids Res 1989 Oct 25;17(20):8033-45
PubMed ID: 2530497