Pseudomonas aeruginosa PAO1, PA4285 (recC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4285
Name
recC
Replicon chromosome
Genomic location 4805195 - 4808710 (- strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_252975.1
GI 15599481
Affymetrix PA4285_recC_at
Entrez 881634
GenBank AAG07673.1
INSDC AAG07673.1
NCBI Locus Tag PA4285
protein_id(GenBank) gb|AAG07673.1|AE004844_5|gnl|PseudoCAP|PA4285
TIGR NTL03PA04286
UniParc UPI00000C5C96
UniProtKB Acc Q9HWB5
UniProtKB ID Q9HWB5_PSEAE
UniRef100 UniRef100_Q9HWB5
UniRef50 UniRef50_Q0AAI0
UniRef90 UniRef90_Q9HWB5

Product

Feature Type CDS
Coding Frame 1
Product Name
exodeoxyribonuclease V gamma chain
Product Name Confidence: Class 2
Synonyms 125 kD polypeptide
exonuclease V
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -31.39
Kyte-Doolittle Hydrophobicity Value -0.391
Molecular Weight (kDa) 132.6
Isoelectric Point (pI) 5.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 155 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003888 (531 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4285
Search term: recC

Human Homologs

References

Properties of the recB and recC gene products of Escherichia coli.
Umeno M, Sasaki M, Anai M, Takagi Y
Biochem Biophys Res Commun 1983 Nov 15;116(3):1144-50
PubMed ID: 6316968
Reconstitution of RecBC DNase activity from purified Escherichia coli RecB and RecC proteins.
Hickson ID, Robson CN, Atkinson KE, Hutton L, Emmerson PT
J Biol Chem 1985 Jan 25;260(2):1224-9
PubMed ID: 3155726
Complete nucleotide sequence of the Escherichia coli recC gene and of the thyA-recC intergenic region.
Finch PW, Wilson RE, Brown K, Hickson ID, Tomkinson AE, Emmerson PT
Nucleic Acids Res 1986 Jun 11;14(11):4437-51
PubMed ID: 3520484