Pseudomonas aeruginosa PAO1, PA4301 (tadB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4301
Name
tadB
Synonym: tadB
Replicon chromosome
Genomic location 4825042 - 4825926 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252991.1
GI 15599497
Affymetrix PA4301_at
DNASU PaCD00007866
Entrez 881596
GenBank AAG07689.1
INSDC AAG07689.1
NCBI Locus Tag PA4301
protein_id(GenBank) gb|AAG07689.1|AE004846_6|gnl|PseudoCAP|PA4301
TIGR NTL03PA04302
UniParc UPI00000C5CA6
UniProtKB Acc Q9HW99
UniProtKB ID Q9HW99_PSEAE
UniRef100 UniRef100_W0YYG9
UniRef50 UniRef50_W0YYG9
UniRef90 UniRef90_W0YYG9

Product

Feature Type CDS
Coding Frame 1
Product Name
TadB
Product Name Confidence: Class 2
Synonyms TadB
Evidence for Translation
Charge (pH 7) 12.61
Kyte-Doolittle Hydrophobicity Value 0.353
Molecular Weight (kDa) 32.4
Isoelectric Point (pI) 10.74

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 185 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003902 (427 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4301
Search term: tadB
Search term: TadB

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
FppA, a novel Pseudomonas aeruginosa prepilin peptidase involved in assembly of type IVb pili.
de Bentzmann S, Aurouze M, Ball G, Filloux A
J Bacteriol 2006 Jul;188(13):4851-60
PubMed ID: 16788194
Mutation analysis of the flp operon in Actinobacillus actinomycetemcomitans.
Wang Y, Chen C
Gene 2005 May 23;351:61-71
PubMed ID: 15837433