Pseudomonas aeruginosa PAO1, PA4334

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4334
Name
Synonym: yfeP
Replicon chromosome
Genomic location 4863273 - 4864529 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253024.1
GI 15599530
Affymetrix PA4334_at
Entrez 881479
GenBank AAG07722.1
INSDC AAG07722.1
NCBI Locus Tag PA4334
protein_id(GenBank) gb|AAG07722.1|AE004849_9|gnl|PseudoCAP|PA4334
TIGR NTL03PA04335
UniParc UPI000012F2A6
UniProtKB Acc Q9RPF3
UniProtKB ID MNTH1_PSEAE
UniRef100 UniRef100_Q9RPF3
UniRef50 UniRef50_Q9RPF3
UniRef90 UniRef90_Q9RPF3

Product

Feature Type CDS
Coding Frame 1
Product Name
probable transport protein
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 2.34
Kyte-Doolittle Hydrophobicity Value 0.798
Molecular Weight (kDa) 44.4
Isoelectric Point (pI) 8.09

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 304 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003930 (412 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4334

Human Homologs

Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 3.4e-54
Percent Identity: 34.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 3.4e-54
Percent Identity: 34.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 3.4e-54
Percent Identity: 34.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 3.4e-54
Percent Identity: 34.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 3.4e-54
Percent Identity: 34.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 3.4e-54
Percent Identity: 34.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 3.4e-54
Percent Identity: 34.2
Ensembl 110, assembly GRCh38.p14
solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908]
E-value: 3.4e-54
Percent Identity: 34.2

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295