Pseudomonas aeruginosa PAO1, PA4352

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4352
Name
Replicon chromosome
Genomic location 4880318 - 4881178 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253042.1
GI 15599548
Affymetrix PA4352_at
Entrez 881434
GenBank AAG07740.1
INSDC AAG07740.1
NCBI Locus Tag PA4352
protein_id(GenBank) gb|AAG07740.1|AE004851_8|gnl|PseudoCAP|PA4352
TIGR NTL03PA04353
UniParc UPI00000C5CD7
UniProtKB Acc Q9HW49
UniProtKB ID Q9HW49_PSEAE
UniRef100 UniRef100_Q9HW49
UniRef50 UniRef50_Q9HW49
UniRef90 UniRef90_Q9HW49

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Detected using LC-MS/MS (30.97 kDa, PMID:21751344)
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.06
Kyte-Doolittle Hydrophobicity Value 0.096
Molecular Weight (kDa) 31.0
Isoelectric Point (pI) 6.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Vesicle Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 328 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003945 (328 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4352

Human Homologs

References

Structure-based assignment of the biochemical function of a hypothetical protein: a test case of structural genomics.
Zarembinski TI, Hung LW, Mueller-Dieckmann HJ, Kim KK, Yokota H, Kim R, Kim SH
Proc Natl Acad Sci U S A 1998 Dec 22;95(26):15189-93
PubMed ID: 9860944
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344