Pseudomonas aeruginosa PAO1, PA4408 (ftsA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4408
Name
ftsA
Replicon chromosome
Genomic location 4940535 - 4941788 (- strand)

Cross-References

RefSeq NP_253098.1
GI 15599604
Affymetrix PA4408_ftsA_at
Entrez 881321
GenBank AAG07796.1
INSDC AAG07796.1
NCBI Locus Tag PA4408
protein_id(GenBank) gb|AAG07796.1|AE004856_7|gnl|PseudoCAP|PA4408
TIGR NTL03PA04409
UniParc UPI000012ACB3
UniProtKB Acc P47203
UniProtKB ID FTSA_PSEAE
UniRef100 UniRef100_P47203
UniRef50 UniRef50_P47203
UniRef90 UniRef90_P47203

Product

Feature Type CDS
Coding Frame 1
Product Name
cell division protein FtsA
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -11.24
Kyte-Doolittle Hydrophobicity Value 0.038
Molecular Weight (kDa) 44.6
Isoelectric Point (pI) 4.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 461 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003998 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4408
Search term: ftsA

Human Homologs

References

DNA sequence and transcriptional organization of essential cell division genes ftsQ and ftsA of Escherichia coli: evidence for overlapping transcriptional units.
Robinson AC, Kenan DJ, Hatfull GF, Sullivan NF, Spiegelberg R, Donachie WD
J Bacteriol 1984 Nov;160(2):546-55
PubMed ID: 6094474
Structure and expression of the cell division genes ftsQ, ftsA and ftsZ.
Yi QM, Rockenbach S, Ward JE Jr, Lutkenhaus J
J Mol Biol 1985 Aug 5;184(3):399-412
PubMed ID: 2995680
Mapping and characterization of mutants of the Escherichia coli cell division gene, ftsA.
Robinson AC, Begg KJ, Sweeney J, Condie A, Donachie WD
Mol Microbiol 1988 Sep;2(5):581-8
PubMed ID: 2846985
Localization of FtsI (PBP3) to the septal ring requires its membrane anchor, the Z ring, FtsA, FtsQ, and FtsL.
Weiss DS, Chen JC, Ghigo JM, Boyd D, Beckwith J
J Bacteriol 1999 Jan;181(2):508-20
PubMed ID: 9882665