Pseudomonas aeruginosa PAO1, PA4413 (ftsW)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA4413
Name
ftsW
Replicon chromosome
Genomic location 4946131 - 4947330 (- strand)

Cross-References

RefSeq NP_253103.1
GI 15599609
Affymetrix PA4413_ftsW_at
Entrez 881267
GenBank AAG07801.1
INSDC AAG07801.1
NCBI Locus Tag PA4413
protein_id(GenBank) gb|AAG07801.1|AE004856_12|gnl|PseudoCAP|PA4413
TIGR NTL03PA04414
UniParc UPI00000C5D02
UniProtKB Acc Q9HW00
UniProtKB ID Q9HW00_PSEAE
UniRef100 UniRef100_Q9HW00
UniRef50 UniRef50_E1V9L1
UniRef90 UniRef90_Q9HW00

Product

Feature Type CDS
Coding Frame 1
Product Name
cell division protein FtsW
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -0.23
Kyte-Doolittle Hydrophobicity Value 0.726
Molecular Weight (kDa) 43.8
Isoelectric Point (pI) 6.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 575 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004003 (549 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4413
Search term: ftsW

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Structural similarity among Escherichia coli FtsW and RodA proteins and Bacillus subtilis SpoVE protein, which function in cell division, cell elongation, and spore formation, respectively.
Ikeda M, Sato T, Wachi M, Jung HK, Ishino F, Kobayashi Y, Matsuhashi M
J Bacteriol 1989 Nov;171(11):6375-8
PubMed ID: 2509435
Identification of FtsW and characterization of a new ftsW division mutant of Escherichia coli.
Khattar MM, Begg KJ, Donachie WD
J. Bacteriol. 1994 Dec;176(23):7140-7
PubMed ID: 7961485
Two polypeptide products of the Escherichia coli cell division gene ftsW and a possible role for FtsW in FtsZ function.
Khattar MM, Addinall SG, Stedul KH, Boyle DS, Lutkenhaus J, Donachie WD
J. Bacteriol. 1997 Feb;179(3):784-93
PubMed ID: 9006034
ftsW is an essential cell-division gene in Escherichia coli.
Boyle DS, Khattar MM, Addinall SG, Lutkenhaus J, Donachie WD
Mol. Microbiol. 1997 Jun;24(6):1263-73
PubMed ID: 9218774