Pseudomonas aeruginosa PAO1, PA4419 (ftsL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4419
Name
ftsL
Replicon chromosome
Genomic location 4954340 - 4954633 (- strand)

Cross-References

RefSeq NP_253109.1
GI 15599615
Affymetrix PA4419_ftsL_at
DNASU PaCD00007914
Entrez 881233
GenBank AAG07807.1
INSDC AAG07807.1
NCBI Locus Tag PA4419
protein_id(GenBank) gb|AAG07807.1|AE004856_18|gnl|PseudoCAP|PA4419
TIGR NTL03PA04420
UniParc UPI00000C5D05
UniProtKB Acc Q9HVZ6
UniProtKB ID FTSL_PSEAE
UniRef100 UniRef100_Q9HVZ6
UniRef50 UniRef50_Q9HVZ6
UniRef90 UniRef90_Q9HVZ6

Product

Feature Type CDS
Coding Frame 1
Product Name
cell division protein FtsL
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 3.22
Kyte-Doolittle Hydrophobicity Value 0.151
Molecular Weight (kDa) 11.1
Isoelectric Point (pI) 9.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
8BH1 MEMBRANE PROTEIN 10/28/22 Core divisome complex FtsWIQBL from Pseudomonas aeruginosa Pseudomonas aeruginosa PAO1 3.8 ELECTRON MICROSCOPY 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 85 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004009 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4419
Search term: ftsL

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Nucleotide sequence of the regulatory region of the gene pbpB of Escherichia coli.
Gómez MJ, Fluoret B, van Heijenoort J, Ayala JA
Nucleic Acids Res 1990 May 11;18(9):2813
PubMed ID: 2187182
FtsL, an essential cytoplasmic membrane protein involved in cell division in Escherichia coli.
Guzman LM, Barondess JJ, Beckwith J
J Bacteriol 1992 Dec;174(23):7716-28
PubMed ID: 1332942