Pseudomonas aeruginosa PAO1, PA4427 (sspB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4427
Name
sspB
Replicon chromosome
Genomic location 4961151 - 4961558 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253117.1
GI 15599623
Affymetrix PA4427_sspB_at
DNASU PaCD00007918
Entrez 881226
GenBank AAG07815.1
INSDC AAG07815.1
NCBI Locus Tag PA4427
protein_id(GenBank) gb|AAG07815.1|AE004857_6|gnl|PseudoCAP|PA4427
TIGR NTL03PA04428
UniParc UPI00000C5D08
UniProtKB Acc Q9HVY8
UniProtKB ID Q9HVY8_PSEAE
UniRef100 UniRef100_A6VBA0
UniRef50 UniRef50_Q4K6H8
UniRef90 UniRef90_W0Z0J7

Product

Feature Type CDS
Coding Frame 1
Product Name
stringent starvation protein B
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -8.32
Kyte-Doolittle Hydrophobicity Value -0.276
Molecular Weight (kDa) 14.5
Isoelectric Point (pI) 4.34

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 141 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004017 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4427
Search term: sspB

Human Homologs

References

Null mutation in the stringent starvation protein of Escherichia coli disrupts lytic development of bacteriophage P1.
Williams MD, Fuchs JA, Flickinger MC
Gene 1991 Dec 20;109(1):21-30
PubMed ID: 1721886
Starvation-induced expression of SspA and SspB: the effects of a null mutation in sspA on Escherichia coli protein synthesis and survival during growth and prolonged starvation.
Williams MD, Ouyang TX, Flickinger MC
Mol Microbiol 1994 Mar;11(6):1029-43
PubMed ID: 8022275
The complete genome sequence of Escherichia coli K-12.
Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y
Science 1997 Sep 5;277(5331):1453-62
PubMed ID: 9278503