Pseudomonas aeruginosa PAO1, PA4452

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4452
Name
Replicon chromosome
Genomic location 4985847 - 4986155 (- strand)

Cross-References

RefSeq NP_253142.1
GI 15599648
Affymetrix PA4452_at
DNASU PaCD00007928
Entrez 880993
GenBank AAG07840.1
INSDC AAG07840.1
NCBI Locus Tag PA4452
protein_id(GenBank) gb|AAG07840.1|AE004859_9|gnl|PseudoCAP|PA4452
TIGR NTL03PA04453
UniParc UPI00000C5D17
UniProtKB Acc Q9HVW5
UniProtKB ID Q9HVW5_PSEAE
UniRef100 UniRef100_Q9HVW5
UniRef50 UniRef50_Q4KI77
UniRef90 UniRef90_Q9HVW5

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.04
Kyte-Doolittle Hydrophobicity Value 0.160
Molecular Weight (kDa) 10.8
Isoelectric Point (pI) 5.13

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7CHA MEMBRANE PROTEIN 07/05/20 Cryo-EM structure of P.aeruginosa MlaFEBD with AMPPNP Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); Pseudomonas aeruginosa PAO1 3.9 ELECTRON MICROSCOPY 100.0
7CH9 MEMBRANE PROTEIN 07/05/20 Cryo-EM structure of P.aeruginosa MlaFEBD Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 3.5 ELECTRON MICROSCOPY 100.0
7CH8 MEMBRANE PROTEIN 07/05/20 Cryo-EM structure of P.aeruginosa MlaFEBD with ADP-V Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 3.9 ELECTRON MICROSCOPY 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 15 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004041 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4452

Human Homologs

References

No references are associated with this feature.