Pseudomonas aeruginosa PAO1, PA4475

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4475
Name
Replicon chromosome
Genomic location 5003900 - 5004748 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253165.1
GI 15599671
Affymetrix PA4475_at
Entrez 881031
GenBank AAG07863.1
INSDC AAG07863.1
NCBI Locus Tag PA4475
protein_id(GenBank) gb|AAG07863.1|AE004861_4|gnl|PseudoCAP|PA4475
TIGR NTL03PA04476
UniParc UPI00000C5D29
UniProtKB Acc Q9HVU6
UniProtKB ID Q9HVU6_PSEAE
UniRef100 UniRef100_W0YZ38
UniRef50 UniRef50_G8Q9B9
UniRef90 UniRef90_A2ICY3

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.64
Kyte-Doolittle Hydrophobicity Value -0.147
Molecular Weight (kDa) 30.7
Isoelectric Point (pI) 6.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 548 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004064 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4475

Human Homologs

Ensembl 110, assembly GRCh38.p14
nitrilase 1 [Source:HGNC Symbol;Acc:HGNC:7828]
E-value: 3.2e-48
Percent Identity: 42.4
Ensembl 110, assembly GRCh38.p14
nitrilase 1 [Source:HGNC Symbol;Acc:HGNC:7828]
E-value: 3.2e-48
Percent Identity: 42.4
Ensembl 110, assembly GRCh38.p14
nitrilase 1 [Source:HGNC Symbol;Acc:HGNC:7828]
E-value: 3.2e-48
Percent Identity: 42.4

References

No references are associated with this feature.