Pseudomonas aeruginosa PAO1, PA4477 (cafA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4477
Name
cafA
Replicon chromosome
Genomic location 5008643 - 5010100 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253167.1
GI 15599673
Affymetrix PA4477_cafA_at
Entrez 881046
GenBank AAG07865.1
INSDC AAG07865.1
NCBI Locus Tag PA4477
protein_id(GenBank) gb|AAG07865.1|AE004861_6|gnl|PseudoCAP|PA4477
TIGR NTL03PA04478
UniParc UPI00000C5D2B
UniProtKB Acc Q9HVU4
UniProtKB ID Q9HVU4_PSEAE
UniRef100 UniRef100_W0Z0U2
UniRef50 UniRef50_P0A9J2
UniRef90 UniRef90_A0A024HLZ2

Product

Feature Type CDS
Coding Frame 1
Product Name
cytoplasmic axial filament protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -13.97
Kyte-Doolittle Hydrophobicity Value -0.153
Molecular Weight (kDa) 54.7
Isoelectric Point (pI) 5.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 497 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004066 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4477
Search term: cafA

Human Homologs

References

Cytoplasmic axial filaments in Escherichia coli cells: possible function in the mechanism of chromosome segregation and cell division.
Okada Y, Wachi M, Hirata A, Suzuki K, Nagai K, Matsuhashi M
J Bacteriol 1994 Feb;176(3):917-22
PubMed ID: 8300545
Possible function of the cytoplasmic axial filaments in chromosomal segregation and cellular division of Escherichia coli.
Okada Y, Shibata T, Matsuhashi M
Sci Prog 1993-1994;77 ( Pt 3-4):253-64
PubMed ID: 7725080
The complete genome sequence of Escherichia coli K-12.
Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y
Science 1997 Sep 5;277(5331):1453-62
PubMed ID: 9278503