Pseudomonas aeruginosa PAO1, PA4499 (psdR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4499
Name
psdR
Replicon chromosome
Genomic location 5036245 - 5036808 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253189.1
GI 15599695
Affymetrix PA4499_at
DNASU PaCD00007948
Entrez 881061
GenBank AAG07887.1
INSDC AAG07887.1
NCBI Locus Tag PA4499
protein_id(GenBank) gb|AAG07887.1|AE004863_7|gnl|PseudoCAP|PA4499
TIGR NTL03PA04500
UniParc UPI00000C5D3B
UniProtKB Acc Q9HVS2
UniProtKB ID Q9HVS2_PSEAE
UniRef100 UniRef100_W0Z0U8
UniRef50 UniRef50_A4XQJ4
UniRef90 UniRef90_B7V039

Product

Feature Type CDS
Coding Frame 1
Product Name
Pseudomonas dipeptide regulator, PdsR
Product Name Confidence: Class 1
Synonyms probable transcriptional regulator
Evidence for Translation
Charge (pH 7) -2.60
Kyte-Doolittle Hydrophobicity Value -0.276
Molecular Weight (kDa) 20.4
Isoelectric Point (pI) 6.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 285 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004087 (331 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4499
Search term: psdR

Human Homologs

References

Genetic analysis of genes involved in dipeptide metabolism and cytotoxicity in Pseudomonas aeruginosa PAO1.
Kiely PD, O'Callaghan J, Abbas A, O'Gara F
Microbiology (Reading) 2008 Aug;154(Pt 8):2209-2218
PubMed ID: 18667554