Pseudomonas aeruginosa PAO1, PA4513

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4513
Name
Synonym: piuB
Replicon chromosome
Genomic location 5050848 - 5053400 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253203.1
GI 15599709
Affymetrix PA4513_at
Entrez 881111
GenBank AAG07901.1
INSDC AAG07901.1
NCBI Locus Tag PA4513
protein_id(GenBank) gb|AAG07901.1|AE004865_2|gnl|PseudoCAP|PA4513
TIGR NTL03PA04514
UniParc UPI00000C5D49
UniProtKB Acc Q9HVQ8
UniProtKB ID Q9HVQ8_PSEAE
UniRef100 UniRef100_O68591
UniRef50 UniRef50_K9NEA4
UniRef90 UniRef90_A0A077JR35

Product

Feature Type CDS
Coding Frame 1
Product Name
probable oxidoreductase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.93
Kyte-Doolittle Hydrophobicity Value -0.146
Molecular Weight (kDa) 94.2
Isoelectric Point (pI) 7.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 309 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004097 (525 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4513

Human Homologs

Ensembl 110, assembly GRCh38.p14
cytochrome p450 oxidoreductase [Source:HGNC Symbol;Acc:HGNC:9208]
E-value: 6.8e-17
Percent Identity: 31.8
Ensembl 110, assembly GRCh38.p14
cytochrome p450 oxidoreductase [Source:HGNC Symbol;Acc:HGNC:9208]
E-value: 6.8e-17
Percent Identity: 31.8
Ensembl 110, assembly GRCh38.p14
cytochrome p450 oxidoreductase [Source:HGNC Symbol;Acc:HGNC:9208]
E-value: 6.8e-17
Percent Identity: 31.8
Ensembl 110, assembly GRCh38.p14
cytochrome p450 oxidoreductase [Source:HGNC Symbol;Acc:HGNC:9208]
E-value: 6.8e-17
Percent Identity: 31.8
Ensembl 110, assembly GRCh38.p14
cytochrome p450 oxidoreductase [Source:HGNC Symbol;Acc:HGNC:9208]
E-value: 6.8e-17
Percent Identity: 31.8
Ensembl 110, assembly GRCh38.p14
cytochrome p450 oxidoreductase [Source:HGNC Symbol;Acc:HGNC:9208]
E-value: 6.8e-17
Percent Identity: 31.8
Ensembl 110, assembly GRCh38.p14
cytochrome p450 oxidoreductase [Source:HGNC Symbol;Acc:HGNC:9208]
E-value: 6.8e-17
Percent Identity: 31.8

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: cycle selection of iron-regulated genes.
Ochsner UA, Vasil ML
Proc Natl Acad Sci U S A 1996 Apr 30;93(9):4409-14
PubMed ID: 8633080