Pseudomonas aeruginosa PAO1, PA4581 (rtcR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4581
Name
rtcR
Replicon chromosome
Genomic location 5129173 - 5130768 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253271.1
GI 15599777
Affymetrix PA4581_rtcR_at
Entrez 880996
GenBank AAG07969.1
INSDC AAG07969.1
NCBI Locus Tag PA4581
protein_id(GenBank) gb|AAG07969.1|AE004871_9|gnl|PseudoCAP|PA4581
TIGR NTL03PA04582
UniParc UPI00000C5D73
UniProtKB Acc Q9HVK3
UniProtKB ID Q9HVK3_PSEAE
UniRef100 UniRef100_W0YZW2
UniRef50 UniRef50_P38035
UniRef90 UniRef90_A6VBW8

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator RtcR
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 3.33
Kyte-Doolittle Hydrophobicity Value -0.395
Molecular Weight (kDa) 60.2
Isoelectric Point (pI) 8.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 430 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004239 (340 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4581
Search term: rtcR

Human Homologs

References

Characterization of the Escherichia coli RNA 3'-terminal phosphate cyclase and its sigma54-regulated operon.
Genschik P, Drabikowski K, Filipowicz W
J Biol Chem 1998 Sep 25;273(39):25516-26
PubMed ID: 9738023