Pseudomonas aeruginosa PAO1, PA4582

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4582
Name
Replicon chromosome
Genomic location 5131428 - 5132573 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253272.1
GI 15599778
Affymetrix PA4582_at
DNASU PaCD00007985
Entrez 881002
GenBank AAG07970.1
INSDC AAG07970.1
NCBI Locus Tag PA4582
protein_id(GenBank) gb|AAG07970.1|AE004872_1|gnl|PseudoCAP|PA4582
TIGR NTL03PA04583
UniParc UPI00000C5D74
UniProtKB Acc Q9HVK2
UniProtKB ID Q9HVK2_PSEAE
UniRef100 UniRef100_Q9HVK2
UniRef50 UniRef50_J2L8I8
UniRef90 UniRef90_Q9HVK2

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (43.09 kDa, PMID:21751344)
Charge (pH 7) -1.26
Kyte-Doolittle Hydrophobicity Value -0.250
Molecular Weight (kDa) 43.1
Isoelectric Point (pI) 6.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Vesicle Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 258 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004240 (307 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4582

Human Homologs

References

Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344