Pseudomonas aeruginosa PAO1, PA4606

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4606
Name
Synonym: cstA
Replicon chromosome
Genomic location 5163788 - 5165854 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253296.1
GI 15599802
Affymetrix PA4606_at
Entrez 881098
GenBank AAG07994.1
INSDC AAG07994.1
NCBI Locus Tag PA4606
protein_id(GenBank) gb|AAG07994.1|AE004874_7|gnl|PseudoCAP|PA4606
TIGR NTL03PA04607
UniParc UPI00000C5D85
UniProtKB Acc Q9HVI3
UniProtKB ID Q9HVI3_PSEAE
UniRef100 UniRef100_W0YZZ8
UniRef50 UniRef50_Q4K5R3
UniRef90 UniRef90_Q02G71

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.31
Kyte-Doolittle Hydrophobicity Value 0.792
Molecular Weight (kDa) 73.5
Isoelectric Point (pI) 7.70

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 301 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004262 (520 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4606

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Molecular and functional characterization of a carbon starvation gene of Escherichia coli.
Schultz JE, Matin A
J Mol Biol 1991 Mar 5;218(1):129-40
PubMed ID: 1848300