Pseudomonas aeruginosa PAO1, PA4609 (radA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4609
Name
radA
Synonym: sms
Replicon chromosome
Genomic location 5167284 - 5168645 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253299.1
GI 15599805
Affymetrix PA4609_radA_at
Entrez 881107
GenBank AAG07997.1
INSDC AAG07997.1
NCBI Locus Tag PA4609
protein_id(GenBank) gb|AAG07997.1|AE004875_3|gnl|PseudoCAP|PA4609
TIGR NTL03PA04610
UniParc UPI0000133098
UniProtKB Acc P96963
UniProtKB ID RADA_PSEAE
UniRef100 UniRef100_P96963
UniRef50 UniRef50_P45266
UniRef90 UniRef90_P96963

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA repair protein RadA
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.45
Kyte-Doolittle Hydrophobicity Value 0.033
Molecular Weight (kDa) 48.4
Isoelectric Point (pI) 6.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 570 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004264 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4609
Search term: radA

Human Homologs

References

Escherichia coli DNA repair genes radA and sms are the same gene.
Song Y, Sargentini NJ
J Bacteriol 1996 Aug;178(16):5045-8
PubMed ID: 8759876