Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4667
|
Name |
lbcA
|
Replicon | chromosome |
Genomic location | 5234997 - 5236769 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Comment | Binding partner of CtpA (PA5134), required for CtpA proteolytic activity |
RefSeq | NP_253356.1 |
GI | 15599862 |
Affymetrix | PA4667_at |
Entrez | 881370 |
GenBank | AAG08054.1 |
INSDC | AAG08054.1 |
NCBI Locus Tag | PA4667 |
protein_id(GenBank) | gb|AAG08054.1|AE004880_10|gnl|PseudoCAP|PA4667 |
TIGR | NTL03PA04668 |
UniParc | UPI000013A09A |
UniProtKB Acc | P42810 |
UniProtKB ID | Y4667_PSEAE |
UniRef100 | UniRef100_P42810 |
UniRef50 | UniRef50_P42810 |
UniRef90 | UniRef90_P42810 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
LbcA
|
Synonyms |
lipoprotein binding partner of CtpA |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
Detected using LC-MS/MS (66.29 kDa, PMID:21751344)
|
Charge (pH 7) | -19.61 |
Kyte-Doolittle Hydrophobicity Value | -0.524 |
Molecular Weight (kDa) | 66.3 |
Isoelectric Point (pI) | 4.83 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
7RQF | PROTEIN BINDING | 08/06/21 | Crystal Structure of LbcA (lipoprotein binding partner of CtpA) of Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 3.5 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 270 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004317 (537 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4667
Search term: lbcA
Search term: LbcA
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
|
A Proteolytic Complex Targets Multiple Cell Wall Hydrolases in Pseudomonas aeruginosa.
Srivastava D, Seo J, Rimal B, Kim SJ, Zhen S, Darwin AJ
mBio 2018 Jul 17;9(4)
PubMed ID: 30018106
|