Pseudomonas aeruginosa PAO1, PA4688 (hitB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4688
Name
hitB
Replicon chromosome
Genomic location 5258724 - 5260262 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253377.1
GI 15599883
Affymetrix PA4688_hitB_at
Entrez 881460
GenBank AAG08075.1
INSDC AAG08075.1
NCBI Locus Tag PA4688
protein_id(GenBank) gb|AAG08075.1|AE004882_6|gnl|PseudoCAP|PA4688
TIGR NTL03PA04689
UniParc UPI00000C5DC8
UniProtKB Acc Q9HVA7
UniProtKB ID Q9HVA7_PSEAE
UniRef100 UniRef100_Q9HVA7
UniRef50 UniRef50_Q9HVA7
UniRef90 UniRef90_Q9HVA7

Product

Feature Type CDS
Coding Frame 1
Product Name
iron (III)-transport system permease HitB
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 18.30
Kyte-Doolittle Hydrophobicity Value 0.773
Molecular Weight (kDa) 56.1
Isoelectric Point (pI) 10.27

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 499 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004338 (456 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4688
Search term: hitB

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295