Pseudomonas aeruginosa PAO1, PA4721

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4721
Name
Synonym: sfsA
Replicon chromosome
Genomic location 5300314 - 5301021 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253409.1
GI 15599915
Affymetrix PA4721_at
DNASU PaCD00008050
Entrez 881588
GenBank AAG08107.1
INSDC AAG08107.1
NCBI Locus Tag PA4721
protein_id(GenBank) gb|AAG08107.1|AE004885_12|gnl|PseudoCAP|PA4721
TIGR NTL03PA04722
UniParc UPI00001358D1
UniProtKB Acc Q9HV77
UniProtKB ID SFSA_PSEAE
UniRef100 UniRef100_Q9HV77
UniRef50 UniRef50_Q9HV77
UniRef90 UniRef90_Q9HV77

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) -0.67
Kyte-Doolittle Hydrophobicity Value -0.163
Molecular Weight (kDa) 25.8
Isoelectric Point (pI) 6.54

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 263 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004367 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4721

Human Homologs

References

Nucleotide sequence and characterization of the sfs1 gene: sfs1 is involved in CRP*-dependent mal gene expression in Escherichia coli.
Kawamukai M, Utsumi R, Takeda K, Higashi A, Matsuda H, Choi YL, Komano T
J Bacteriol 1991 Apr;173(8):2644-8
PubMed ID: 2013578