Pseudomonas aeruginosa PAO1, PA4768 (smpB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4768
Name
smpB
Replicon chromosome
Genomic location 5353783 - 5354262 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253456.1
GI 15599962
Affymetrix PA4768_smpB_at
DNASU PaCD00008068
Entrez 881797
GenBank AAG08154.1
INSDC AAG08154.1
NCBI Locus Tag PA4768
protein_id(GenBank) gb|AAG08154.1|AE004890_7|gnl|PseudoCAP|PA4768
TIGR NTL03PA04769
UniParc UPI0000136027
UniProtKB Acc Q9HV40
UniProtKB ID SSRP_PSEAE
UniRef100 UniRef100_A6VCM5
UniRef50 UniRef50_A6VCM5
UniRef90 UniRef90_A6VCM5

Product

Feature Type CDS
Coding Frame 1
Product Name
SmpB protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 13.85
Kyte-Doolittle Hydrophobicity Value -0.583
Molecular Weight (kDa) 18.0
Isoelectric Point (pI) 10.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 591 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004412 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4768
Search term: smpB
Search term: SmpB protein

Human Homologs

References

SmpB, a unique RNA-binding protein essential for the peptide-tagging activity of SsrA (tmRNA).
Karzai AW, Susskind MM, Sauer RT
EMBO J 1999 Jul 1;18(13):3793-9
PubMed ID: 10393194