Pseudomonas aeruginosa PAO1, PA4778 (cueR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4778
Name
cueR
Synonym: ybbI
Replicon chromosome
Genomic location 5366257 - 5366655 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253466.1
GI 15599972
Affymetrix PA4778_at
DNASU PaCD00008071
Entrez 881842
GenBank AAG08164.1
INSDC AAG08164.1
NCBI Locus Tag PA4778
protein_id(GenBank) gb|AAG08164.1|AE004891_6|gnl|PseudoCAP|PA4778
TIGR NTL03PA04779
UniParc UPI000013A346
UniProtKB Acc Q9HV30
UniProtKB ID Y4778_PSEAE
UniRef100 UniRef100_Q9HV30
UniRef50 UniRef50_Q9X5V4
UniRef90 UniRef90_Q9HV30

Product

Feature Type CDS
Coding Frame 1
Product Name
CueR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.31
Kyte-Doolittle Hydrophobicity Value -0.591
Molecular Weight (kDa) 15.0
Isoelectric Point (pI) 7.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 396 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004420 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4778
Search term: cueR
Search term: CueR

Human Homologs

References

Quorum-sensing regulation of a copper toxicity system in Pseudomonas aeruginosa.
Thaden JT, Lory S, Gardner TS
J Bacteriol 2010 May;192(10):2557-68
PubMed ID: 20233934