Pseudomonas aeruginosa PAO1, PA4821

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4821
Name
Synonym: dinF
Replicon chromosome
Genomic location 5410876 - 5412237 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253508.1
GI 15600014
Affymetrix PA4821_at
Entrez 880059
GenBank AAG08206.1
INSDC AAG08206.1
NCBI Locus Tag PA4821
protein_id(GenBank) gb|AAG08206.1|AE004895_6|gnl|PseudoCAP|PA4821
TIGR NTL03PA04822
UniParc UPI00000C5E22
UniProtKB Acc Q9HUY9
UniProtKB ID Q9HUY9_PSEAE
UniRef100 UniRef100_Q9HUY9
UniRef50 UniRef50_Q48DJ8
UniRef90 UniRef90_Q9HUY9

Product

Feature Type CDS
Coding Frame 1
Product Name
probable transporter
Product Name Confidence: Class 3
Synonyms DNA-damage-inducible protein F
Evidence for Translation
Charge (pH 7) 15.05
Kyte-Doolittle Hydrophobicity Value 0.657
Molecular Weight (kDa) 48.6
Isoelectric Point (pI) 11.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 303 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004453 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4821

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli.
Kenyon CJ, Walker GC
Proc Natl Acad Sci U S A 1980 May;77(5):2819-23
PubMed ID: 6771759
Isolation and characterization of Tn5 insertion mutations in the lexA gene of Escherichia coli.
Krueger JH, Elledge SJ, Walker GC
J Bacteriol 1983 Mar;153(3):1368-78
PubMed ID: 6298183