Pseudomonas aeruginosa PAO1, PA4850 (prmA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4850
Name
prmA
Replicon chromosome
Genomic location 5445199 - 5446083 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_253537.1
GI 15600043
Affymetrix PA4850_prmA_at
Entrez 878325
GenBank AAG08235.1
INSDC AAG08235.1
NCBI Locus Tag PA4850
protein_id(GenBank) gb|AAG08235.1|AE004898_6|gnl|PseudoCAP|PA4850
TIGR NTL03PA04851
UniParc UPI00000C5E3A
UniProtKB Acc Q9HUW3
UniProtKB ID PRMA_PSEAE
UniRef100 UniRef100_B7V1R2
UniRef50 UniRef50_Q489G6
UniRef90 UniRef90_B7V1R2

Product

Feature Type CDS
Coding Frame 1
Product Name
ribosomal protein L11 methyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -24.36
Kyte-Doolittle Hydrophobicity Value -0.035
Molecular Weight (kDa) 32.0
Isoelectric Point (pI) 4.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 507 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004479 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4850
Search term: prmA

Human Homologs

References

Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994