Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4944
|
Name |
hfq
Synonym: hfq |
Replicon | chromosome |
Genomic location | 5548397 - 5548645 (- strand) |
RefSeq | NP_253631.1 |
GI | 15600137 |
Affymetrix | PA4944_at |
Entrez | 878015 |
GenBank | AAG08329.1 |
INSDC | AAG08329.1 |
NCBI Locus Tag | PA4944 |
protein_id(GenBank) | gb|AAG08329.1|AE004907_7|gnl|PseudoCAP|PA4944 |
TIGR | NTL03PA04945 |
UniParc | UPI000012C6A3 |
UniProtKB Acc | Q9HUM0 |
UniProtKB ID | HFQ_PSEAE |
UniRef100 | UniRef100_A6VD57 |
UniRef50 | UniRef50_Q9ZI76 |
UniRef90 | UniRef90_Q4KJ73 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Hfq
|
Synonyms |
Hfq |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 3.46 |
Kyte-Doolittle Hydrophobicity Value | -0.244 |
Molecular Weight (kDa) | 9.1 |
Isoelectric Point (pI) | 10.00 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4J5Y | RNA BINDING PROTEIN | 02/11/13 | Crystal structure of Hfq from Pseudomonas aeruginosa in complex with ATP | Pseudomonas aeruginosa | 2.0953 | X-RAY DIFFRACTION | 100.0 |
8BVJ | RNA BINDING PROTEIN | 12/04/22 | Hfq-Crc-estA translation repression complex | Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT | 4.5 | ELECTRON MICROSCOPY | 100.0 |
8BVH | RNA BINDING PROTEIN | 12/03/22 | Cryo-EM structure of the Hfq-Crc-amiE translation repression assembly. | Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT | 3.6 | ELECTRON MICROSCOPY | 100.0 |
3QUI | RNA BINDING PROTEIN | 02/24/11 | Crystal structure of Pseudomonas aeruginosa Hfq in complex with ADPNP | Pseudomonas aeruginosa | 1.933 | X-RAY DIFFRACTION | 100.0 |
Source 1 | |
Database | Victors : 4214 |
Category | |
Evidence |
ECO:0000015
mutant phenotype evidence
|
Host Organism | Mus musculus |
Notes | |
Reference | 14521880 |
Source 2 | |
Database | Victors : 4214 |
Category | |
Evidence |
ECO:0000015
mutant phenotype evidence
|
Host Organism | Galleria mellonella |
Notes | |
Reference | 14521880 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 282 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004559 (536 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4944
Search term: hfq
Search term: Hfq
|
Hfq-dependent alterations of the transcriptome profile and effects on quorum sensing in Pseudomonas aeruginosa.
Sonnleitner E, Schuster M, Sorger-Domenigg T, Greenberg EP, Bläsi U
Mol Microbiol 2006 Mar;59(5):1542-58
PubMed ID: 16468994
|
Reduced virulence of a hfq mutant of Pseudomonas aeruginosa O1.
Sonnleitner E, Hagens S, Rosenau F, Wilhelm S, Habel A, Jäger KE, Bläsi U
Microb Pathog 2003 Nov;35(5):217-28
PubMed ID: 14521880
|
yst gene expression in Yersinia enterocolitica is positively regulated by a chromosomal region that is highly homologous to Escherichia coli host factor 1 gene (hfq).
Nakao H, Watanabe H, Nakayama S, Takeda T
Mol Microbiol 1995 Dec;18(5):859-65
PubMed ID: 8825090
|
DNA binding properties of the hfq gene product of Escherichia coli.
Takada A, Wachi M, Kaidow A, Takamura M, Nagai K
Biochem Biophys Res Commun 1997 Jul 30;236(3):576-9
PubMed ID: 9245691
|